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EPO-BOOST Research

Active compounds in the patent-pending EPO-BOOST formula are supported by medical research and have been cited in over 5,575 clinical studies. Active components in EPO-BOOST have been demonstrated in university athletes to safely increase blood EPO levels

Erythropoietin Production


4 capsules of EPO-BOOST provide 8 grams of echinacea purpurea

Whitehead M. T., Martin T. D., Webster M. J., & Scheett T. P. (2007). Improved running economy and maximal oxygen consumption after 4-weeks of oral Echinacea supplementation. ACSM Annual Meeting New Orleans, Presentation Number, 908.

PURPOSE. This study investigated the effects of four weeks of oral Echinacea supplementation on erythropoietin, running economy, and VO2max. Males (N = 24) were supplemented with either 8,000 mg/d of Echinacea purpurea (N = 12) or a placebo (N = 12). Blood samples were collected prior to and every seven days during supplementation and analyzed for erythropoietin. Maximal graded exercise tests were administered to measure VO2max, running economy, and heart-rate responses.

RESULTS. The Echinacea condition significantly increased Erythropoietin at days 7, 14, and 21 and VO2max. Running economy improved significantly in the Echinacea condition (indicated by a decrease in submaximal VO2 during the first 2 stages of the graded exercise test).

CONCLUSION. Echinacea purpurea supplementation results in significant increases in erythropoietin, VO2max, and running economy.


Whitehead, M. T., (2006). The effect of four weeks of Echinacea supplementation on erythropoietin and indices of erythropoietic status. Medicine and Science in Sports and Exercise, 38(5), Supplement abstract 2256.

PURPOSE. This study determined whether four weeks of oral Echinacea purpurea supplementation resulted in alterations in erythropoietin, red blood cell count, hematocrit, or hemoglobin. Recreationally active males N = 24) were assigned randomly to either an Echinacea (N = 12) or a placebo (N = 12) group. Participants were supplemented for 28 consecutive days.

RESULTS. Serum erythropoietin was significantly greater in the Echinacea condition than in the placebo group at days, 7, 14, and 21.

CONCLUSION. Echinacea purpurea supplementation for 28 days promoted a significant increase in erythropoietin.


Whitehead, M. T., Martin, T. D., Webster, M. J., & Scheett, T. P. (2005). Two weeks of oral
Echinacea supplementation significantly increases circulating erythropoietin
. Medicine and Science in Sports and Exercise, 37(5), Supplement abstract 231.

STUDY. Healthy active males (N = 24) were assigned randomly to a placebo or an Echinacea
purpurea supplementation group. Subjects received 8 gm/day of one substance for 14 days.

RESULTS. Erythropoietin (EPO) was 44.15% greater in the supplemented group than in the placebo group.

CONCLUSION. Echinacea purpurea stimulates significant EPO increases.

Red Blood Cell Nutrients

Ingredients: Vitamin B-3 (Niacinamide), Vitamin B-6 (Pyridoxine HCl), Folate (Folic Acid), Vitamin B-12 (Cobalamin), Inositol, Boron

2. Agte VV, Paknikar KM, Chiplonkar SA (1997) Effect of nicotinic acid on zinc and iron metabolism. Biometals. 10(4):271-6.

3. Ink SL, Mehansho H, Henderson LM. (1982) The binding of pyridoxal to hemoglobin. J Biol Chem.257(9):4753-7.

4. Woods M, Lessin LS. (1978) Inhibition of erythrocyte sickling in vitro by pyridoxal. J Clin Invest.62(4):888-91.

5. Moestrup SK (2006) New insights into carrier binding and epithelial uptake of the erythropoieticnutrients cobalamin and folate. Curr Opin Hematol. 13(3):119-23.

6. Koury MJ, Ponka P (2004) New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annu Rev Nutr. 2 4:105-31.

7. Kurtoğlu F, Kurtoğlu V, Celik I, Keçeci T, Nizamlioğlu M. (2005) Effects of dietary boron supplementation on some biochemical parameters, peripheral blood lymphocytes, splenic plasma cells and bone characteristics of broiler chicks given diets with adequate or inadequate cholecalciferol (vitamin D3) content. Br Poult Sci. 46(1):87-96.

8. Strunecká A, el Desouki NI, Palecek J, Kmonícková E, Krpejsová L, Potter BV. (1991) The effect of inositol 1,4,5-trisphosphate and inositol 1,4,5-trisphosphorothioate on calcium release and membrane skeleton organization in the human red blood cell. Receptor. 1(3):141-54.

9. Gersonde K, Nicolau C. (1979) Improvement of the red blood cell O2 release capacity by lipid vesiclemediated incorporation of inositol hexaphosphate. Blut. 39(1):1-7.

Iron Availability Complex

Ingredients: Iron, Vitamin C (Ascorbic Acid), Vitamin B-3 (Niacinamide), Nickel, Dandelion Extract,Yellow Dock Extract

10. Koury MJ, Ponka P (2004) New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annu Rev Nutr. 24:105-31.

11. Rozycki VR, Baigorria CM, Freyre MR, Bernard CM, Zannier MS, Charpentier M. (1997) Nutrientcontent in vegetable species from the Argentine Chaco. Arch Latinoam Nutr. 47(3):265-70.

12. Reddy NS, Bhatt G. (2001) Contents of minerals in green leafy vegetables cultivated in soil fortified with different chemical fertilizers. Plant Foods Hum Nutr. 56(1):1-6.

13. Atanassova B.D., Tzatchev KN (2008) Ascorbic acid-important for iron metabolism. Folia Med. Plovdiv. Oct-Dec; 50(4):11-6.

14. Teucher B, Olivares M, Cori H (2004) Enhancers of iron absorption: ascorbic acid and other organic acids. Int J Vitam Nutr Res. Nov; 74(6):403-19.

15. Agte VV, Paknikar KM, Chiplonkar SA (1997) Effect of nicotinic acid on zinc and iron metabolism. Biometals. 10(4):271-6.

16. Cempel M. (2004) Effect of nickel(II) chloride on iron content in rat organs after oral administration. Biol Trace Elem Res. 102(1-3):189-98.

Anti-Inflammatory Complex

Ingredients: Alpha-Lipoic Acid, Lutein, Lycopene, Choline, PABA

17. Zembron-Lacny A, Szyszka K, Szygula Z. (2007) Effect of cysteine derivatives administration in healthy men exposed to intense resistance exercise evaluation of pro-antioxidant ratio. J Physiol Sci. 57(6):343-8.

18. Marangon K, Devaraj S, Tirosh O, Packer L, Jialal I. (1999) Comparison of the effect of alpha-lipoic acid and alpha-tocopherol supplementation on measures of oxidative stress. Free Radic Biol Med. 27(9-10):1114-21.

19. Klebanov GI, Kapitanov AB, Teselkin YuO, Babenkova IV, Zhambalova BA, Lyubitsky OB, Nesterova OA, Vasil'eva OV, Popov IN, Lewin G, Vladimirov YuA. (1998) The antioxidant properties of lycopene. Membr Cell Biol. 12(2):287-300.

20. Santos T, Mesquita R, Martins E Silva J, Saldanha C. (2003) Effects of choline on hemorheological properties and NO metabolism of human erythrocytes. Clin Hemorheol Microcirc. 29(1):41-51.

21. Gaby AR. (2006) Natural remedies for scleroderma. Altern Med Rev. 11(3):188-95.

Legal notice: The patent-pending EPO-BOOST formula is proprietary to Biomedical Research Laboratories, LLC. Biomedical Research Laboratories, LLC has been successful in defending its intellectual property and prosecuting all unauthorized uses or violations to the fullest extent of both domestic and international law.

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